Metal Ion Activation of Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B

Lethal Toxin from Clostridium sordellii (TcsL) and Toxin B from Clostridium difficile (TcdB) belong to the family of the “Large clostridial glycosylating toxins.” These toxins mono-O-glucosylate low molecular weight GTPases of the Rho and Ras families by exploiting UDP-glucose as a hexose donor. Tcs...

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Bibliographic Details
Main Authors: Harald Genth, Ilona Schelle, Ingo Just
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/4/109