Structural insights into thrombolytic activity of destabilase from medicinal leech

Structural insights into thrombolytic activity of destabilase from medicinal leech

Abstract Destabilase from the medical leech Hirudo medicinalis belongs to the family of i-type lysozymes. It has two different enzymatic activities: microbial cell walls destruction (muramidase activity), and dissolution of the stabilized fibrin (isopeptidase activity). Both activities are known to...

Full description

Bibliographic Details
Main Authors: Egor Marin, Daniil A. Kornilov, Sergey S. Bukhdruker, Vladimir A. Aleksenko, Valentin A. Manuvera, Egor V. Zinovev, Kirill V. Kovalev, Mikhail B. Shevtsov, Anna A. Talyzina, Pavel A. Bobrovsky, Pavel K. Kuzmichev, Alexey V. Mishin, Ivan Y. Gushchin, Vassili N. Lazarev, Valentin I. Borshchevskiy
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32459-x

Internet

https://doi.org/10.1038/s41598-023-32459-x

Similar Items