The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease
Glutamate dehydrogenase (GDH) is a hexameric enzyme that catalyzes the reversible conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD(P)+ to NAD(P)H. It is found in all living organisms serving both catabolic and anabolic reactions. In mammalian tissues, oxidative deamination o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2017-02-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-7737/6/1/11 |