Novel Insights into Mice Multi-Organ Metabolism upon Exposure to a Potential Anticancer Pd(II)-Agent

Novel Insights into Mice Multi-Organ Metabolism upon Exposure to a Potential Anticancer Pd(II)-Agent

Pd(II)-compounds are presently regarded as promising anticancer drugs, as an alternative to Pt(II)-based drugs (e.g., cisplatin), which typically trigger severe side-effects and acquired resistance. Dinuclear Pd(II) complexes with biogenic polyamines such as spermine (Pd<sub>2</sub>Spm)...

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Bibliographic Details
Main Authors: Tatiana J. Carneiro, Rita Araújo, Martin Vojtek, Salomé Gonçalves-Monteiro, Carmen Diniz, Ana L. M. Batista de Carvalho, M. Paula M. Marques, Ana M. Gil
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Metabolites
Subjects:
palladium(II)-drugs
Pd<sub>2</sub>Spm
cisplatin
mice
NMR metabolomics
tissue extracts
Online Access:https://www.mdpi.com/2218-1989/11/2/114

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https://www.mdpi.com/2218-1989/11/2/114

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