Elevated serum levels of glial fibrillary acidic protein are associated with covert hepatic encephalopathy in patients with cirrhosis

Elevated serum levels of glial fibrillary acidic protein are associated with covert hepatic encephalopathy in patients with cirrhosis

Background & Aims: Blood biomarkers facilitating the diagnosis of covert hepatic encephalopathy (CHE) in patients with cirrhosis are lacking. Astrocyte swelling is a major component of hepatic encephalopathy. Thus, we hypothesised that glial fibrillary acidic protein (GFAP), the major interm...

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Bibliographic Details
Main Authors: Simon Johannes Gairing, Sven Danneberg, Leonard Kaps, Michael Nagel, Eva Maria Schleicher, Charlotte Quack, Sinah Engel, Stefan Bittner, Peter Robert Galle, Jörn Markus Schattenberg, Marcus-Alexander Wörns, Felix Luessi, Jens Uwe Marquardt, Christian Labenz
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:JHEP Reports
Subjects:
CHE
HE
GFAP
Biomarkers
Complications of cirrhosis
Psychometric hepatic encephalopathy score
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000022

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http://www.sciencedirect.com/science/article/pii/S2589555923000022

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