RNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization

Abstract The Wnt signaling pathway is a crucial regulator of various biological processes, such as development and cancer. The downstream transcription factors in this pathway play a vital role in determining the threshold for signaling induction and the length of the response, which vary depending...

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Bibliographic Details
Main Authors: Youngmu Koo, Wonhee Han, Byeong-Rak Keum, Leila Lutz, Sung Ho Yun, Gun-Hwa Kim, Jin-Kwan Han
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47111-x