High-throughput screening of natural antiviral drug candidates against white spot syndrome virus targeting VP28 in Penaeus monodon: Computational drug design approaches

High-throughput screening of natural antiviral drug candidates against white spot syndrome virus targeting VP28 in Penaeus monodon: Computational drug design approaches

The white spot syndrome virus (WSSV), considered the deadliest pathogen impacting Penaeid shrimp (Penaeus monodon), remains worrisome for the global shrimp industry due to its extreme virulence and mortality rate of up to 100%. To date, there has been no breakthrough in effective antivirals or vacci...

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Bibliographic Details
Main Authors: Md. Touki Tahamid Tusar, Zubaer Hossen, Hafizur Rahman Gazi, Niamul Haq, Abdullah-Al Jubayer, Md Mahmudul Islam, Asura Khanam Lisa, Biswanath Sikdar, Md. Enamul Haque
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Penaeus monodon
White Spot Syndrome Virus
VP28
Virtual screening
Molecular dynamics simulation
MM-PBSA
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X24001586

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http://www.sciencedirect.com/science/article/pii/S1687157X24001586

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