Tauroursodeoxycholic Acid Improves the Survival and Function of Nigral Transplants in a Rat Model of Parkinson's Disease

There is accumulating evidence showing that the majority of cell death in neural grafts results from apoptosis when cells are implanted into the brain. Tauroursodeoxycholic acid (TUDCA), a taurine-conjugated hydrophilic bile acid, has been found to possess antiapoptotic properties. In the present st...

Full description

Bibliographic Details
Main Authors: Wei-Ming Duan, Cecilia M. P. Rodrigures, Li-Ru Zhao, Clifford J. Steer, Walter C. Low Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2002-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096020198389960