A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size

A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size

Lipid droplets (LDs) are the major fat storage organelles in eukaryotic cells, but how their size is regulated is unknown. Using genetic screens in C. elegans for LD morphology defects in intestinal cells, we found that mutations in atlastin, a GTPase required for homotypic fusion of endoplasmic ret...

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Bibliographic Details
Main Authors: Robin W. Klemm, Justin P. Norton, Ronald A. Cole, Chen S. Li, Seong H. Park, Matthew M. Crane, Liying Li, Diana Jin, Alexandra Boye-Doe, Tina Y. Liu, Yoko Shibata, Hang Lu, Tom A. Rapoport, Robert V. Farese, Jr., Craig Blackstone, Yi Guo, Ho Yi Mak
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001976

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http://www.sciencedirect.com/science/article/pii/S2211124713001976

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