Pyruvate protects against experimental stroke via an anti-inflammatory mechanism
Pyruvate, a key intermediate in glucose metabolism, was explored as a potential treatment in models of experimental stroke and inflammation. Pyruvate was administered to rodents after the onset of middle cerebral artery occlusion (MCAO). Since the extent of inflammation is often proportional to the...
Main Authors: | Qing Wang, Michael van Hoecke, Xian Nan Tang, Hokyou Lee, Zheng Zheng, Raymond A. Swanson, Midori A. Yenari |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996109001879 |
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