Novel biallelic MCMDC2 variants were associated with meiotic arrest and nonobstructive azoospermia

Novel biallelic MCMDC2 variants were associated with meiotic arrest and nonobstructive azoospermia

Nonobstructive azoospermia (NOA), one of the most severe types of male infertility, etiology often remains unclear in most cases. Therefore, this study aimed to detect four biallelic detrimental variants (0.5%) in the minichromosome maintenance domain containing 2 (MCMDC2) genes in 768 NOA patients...

Full description

Bibliographic Details
Main Authors: Hao-Wei Bai, Na Li, Yu-Xiang Zhang, Jia-Qiang Luo, Ru-Hui Tian, Peng Li, Yu-Hua Huang, Fu-Rong Bai, Cun-Zhong Deng, Fu-Jun Zhao, Ren Mo, Ning Chi, Yu-Chuan Zhou, Zheng Li, Chen-Cheng Yao, Er-Lei Zhi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Asian Journal of Andrology
Subjects:
genetic variant
mcmdc2
meiotic arrest
nonobstructive azoospermia
Online Access:https://journals.lww.com/10.4103/aja202495

Internet

https://journals.lww.com/10.4103/aja202495

Similar Items