Biological Evaluation of <i>Valeriana</i> Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities—The Case of <i>Valeriana carnosa</i> Sm. (Caprifoliaceae) Studied in Mice

Biological Evaluation of <i>Valeriana</i> Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities—The Case of <i>Valeriana carnosa</i> Sm. (Caprifoliaceae) Studied in Mice

Alzheimer’s disease (AD) is a neurodegenerative disorder whose pathophysiology includes the abnormal accumulation of proteins (e.g., β-amyloid), oxidative stress, and alterations in neurotransmitter levels, mainly acetylcholine. Here we present a comparative study of the effect of extracts obtained...

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Bibliographic Details
Main Authors: Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceuticals
Subjects:
Alzheimer’s disease
medicinal plant
acetylcholinesterase
antioxidant
β-amyloid aggregation
monoamine oxidase
Online Access:https://www.mdpi.com/1424-8247/16/1/129

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https://www.mdpi.com/1424-8247/16/1/129

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