Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology

Swiss-PO is a new web tool to map gene mutations on the 3D structure of corresponding proteins and to intuitively assess the structural implications of protein variants for precision oncology. Swiss-PO is constructed around a manually curated database of 3D structures, variant annotations, and seque...

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Bibliographic Details
Main Authors: Fanny S. Krebs, Vincent Zoete, Maxence Trottet, Timothée Pouchon, Christophe Bovigny, Olivier Michielin
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00156-5