Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function.

Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine, octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated receptor 1 (TAAR1). TAAR1 has been implicated in human conditions including obesity, schizophrenia, depression, fibromyalgia,...

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Bibliographic Details
Main Authors: Xiao Shi, Nicole A R Walter, John H Harkness, Kim A Neve, Robert W Williams, Lu Lu, John K Belknap, Amy J Eshleman, Tamara J Phillips, Aaron Janowsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4816557?pdf=render