Potential Opportunities and Challenges of Deploying Next Generation Sequencing and CRISPR-Cas Systems to Support Diagnostics and Surveillance Towards Malaria Control and Elimination in Africa

Potential Opportunities and Challenges of Deploying Next Generation Sequencing and CRISPR-Cas Systems to Support Diagnostics and Surveillance Towards Malaria Control and Elimination in Africa

Recent developments in molecular biology and genomics have revolutionized biology and medicine mainly in the developed world. The application of next generation sequencing (NGS) and CRISPR-Cas tools is now poised to support endemic countries in the detection, monitoring and control of endemic diseas...

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Main Authors: Beatus M. Lyimo, Zachary R. Popkin-Hall, David J. Giesbrecht, Celine I. Mandara, Rashid A. Madebe, Catherine Bakari, Dativa Pereus, Misago D. Seth, Ramadhan M. Ngamba, Ruth B. Mbwambo, Bronwyn MacInnis, Daniel Mbwambo, Issa Garimo, Frank Chacky, Sijenunu Aaron, Abdallah Lusasi, Fabrizio Molteni, Ritha Njau, Jane A. Cunningham, Samwel Lazaro, Ally Mohamed, Jonathan J. Juliano, Jeffrey A.  Bailey, Deus S. Ishengoma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
next generation sequencing
CRISPR-Cas systems
pathogen genomics
malaria diagnosis
malaria molecular surveillance
Africa
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.757844/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.757844/full

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