CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2

CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2

Background Despite the discovery of the p.V617F in JAK2, the molecular pathogenesis of some chronic myeloproliferative neoplasms remains unclear. Although very rare, different studies have identified CBL (Cas-Br-Murine ecotropic retroviral transforming sequence) mutations in V617FJAK2-negative patie...

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Bibliographic Details
Main Authors: Paula Aranaz, Cristina Hurtado, Ignacio Erquiaga, Itziar Miguéliz, Cristina Ormazábal, Ion Cristobal, Marina García-Delgado, Francisco Javier Novo, José Luis Vizmanos
Format: Article
Language:English
Published: Ferrata Storti Foundation 2012-08-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6385

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https://haematologica.org/article/view/6385

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