Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration

Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration

Purpose: To evaluate associations between rare dysfunctional complement factor I (CFI) genetic variant status and progression to advanced age-related macular degeneration (AAMD), geographic atrophy (GA), and neovascular disease (NV). Design: Prospective, longitudinal study Participants: Patients age...

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Bibliographic Details
Main Authors: Johanna M. Seddon, MD, Bernard Rosner, PhD, Dikha De, MPH, Tianxiao Huan, PhD, Anuja Java, MD, John Atkinson, MD
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Ophthalmology Science
Subjects:
Advanced age-related macular degeneration
Complement factor I
Genetic variants
Geographic atrophy
Neovascular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914522001543

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http://www.sciencedirect.com/science/article/pii/S2666914522001543

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