Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism

Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism

Objective: Non-alcoholic fatty liver disease (NAFLD) is linked to impaired lipid metabolism and systemic insulin resistance, which is partly mediated by altered secretion of liver proteins known as hepatokines. Regular physical activity can resolve NAFLD and improve its metabolic comorbidities, howe...

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Bibliographic Details
Main Authors: William De Nardo, Paula M. Miotto, Jacqueline Bayliss, Shuai Nie, Stacey N. Keenan, Magdalene K. Montgomery, Matthew J. Watt
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Metabolism
Subjects:
Exercise
Hepatokine
Syndecan-4
Non-alcoholic fatty liver disease
Hepatic steatosis
Lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000606

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http://www.sciencedirect.com/science/article/pii/S2212877822000606

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