HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding

<p>Low surface HLA-DR expression is a feature in sepsis. However, the mechanisms that regulate HLA-DR expression have not been elucidated. The current study investigates regulation of HLA-DR gene transcription, post transcriptional events and shedding of surface HLA-DR, as well as the regulati...

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Bibliographic Details
Format: Article
Language:English
Published: Ivyspring International Publisher 2004-07-01
Series:International Journal of Medical Sciences
Subjects:
Online Access:http://www.medsci.org/v01p0126.htm