Mortality and ventilatory effects of central serotonin deficiency during postnatal development depend on age but not sex

Mortality and ventilatory effects of central serotonin deficiency during postnatal development depend on age but not sex

Abstract Serotonin (5‐HT) influences brain development and has predominantly excitatory neuromodulatory effects on the neural respiratory control circuitry. Infants that succumb to sudden infant death syndrome (SIDS) have reduced brainstem 5‐HT levels and Tryptophan hydroxylase 2 (Tph2). Furthermore...

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Bibliographic Details
Main Authors: Gary C. Mouradian Jr., Madeline Kilby, Santiago Alvarez, Kara Kaplan, Matthew R. Hodges
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Physiological Reports
Subjects:
5‐HT
respiratory development
serotonin
tryptophan hydroxylase 2
Online Access:https://doi.org/10.14814/phy2.14946

Internet

https://doi.org/10.14814/phy2.14946

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