Green Bio-Analytical Study of Gabapentin in Human Plasma Coupled with Pharmacokinetic and Bioequivalence Assessment Using UPLC-MS/MS

Green Bio-Analytical Study of Gabapentin in Human Plasma Coupled with Pharmacokinetic and Bioequivalence Assessment Using UPLC-MS/MS

Gabapentin (GAB) is a cyclohexane acetic acid, structurally related to the neurotransmitter gamma-aminobutyric acid (GABA), and considered the principal inhibitory neurotransmitter in the central nervous system (CNS) of mammals. An ultra-performance liquid chromatography–tandem mass spectrophotometr...

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Bibliographic Details
Main Authors: Rehab Moussa Tony, Mohamed A. El Hamd, Mohammed Gamal, Safaa F. Saleh, Nujud Maslamani, Wejdan T. Alsaggaf, Mohamed B. El-Zeiny
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Separations
Subjects:
gabapentin
UPLC-MS/MS
pregabalin
human plasma
pharmacokinetics
bioequivalent study
Online Access:https://www.mdpi.com/2297-8739/10/4/234

Internet

https://www.mdpi.com/2297-8739/10/4/234

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