Evolution of sequence traits of prion-like proteins linked to amyotrophic lateral sclerosis (ALS)

Prions are proteinaceous particles that can propagate an alternative conformation to further copies of the same protein. They have been described in mammals, fungi, bacteria and archaea. Furthermore, across diverse organisms from bacteria to eukaryotes, prion-like proteins that have similar sequence...

Full description

Bibliographic Details
Main Authors: Jiayi Luo, Paul M. Harrison
Format: Article
Language:English
Published: PeerJ Inc. 2022-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14417.pdf