Targeting the Extra-Cellular Matrix—Tumor Cell Crosstalk for Anti-Cancer Therapy: Emerging Alternatives to Integrin Inhibitors

Targeting the Extra-Cellular Matrix—Tumor Cell Crosstalk for Anti-Cancer Therapy: Emerging Alternatives to Integrin Inhibitors

The extracellular matrix (ECM) is a complex network composed of a multitude of different macromolecules. ECM components typically provide a supportive structure to the tissue and engender positional information and crosstalk with neighboring cells in a dynamic reciprocal manner, thereby regulating t...

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Bibliographic Details
Main Authors: Girieca Lorusso, Curzio Rüegg, François Kuonen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
extracellular matrix
tumor
progression
crosstalk
clinical perspectives
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01231/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01231/full

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