Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients

Abstract Edoxaban is an orally active inhibitor of activated factor X (FXa). Population pharmacokinetic (PK) and pharmacodynamic (PD) analyses were performed to characterize the PK and PK–PD relationships of edoxaban in pediatric patients to identify the covariates that may contribute to inter‐subje...

Full description

Bibliographic Details
Main Authors: Peng Zou, Akhilesh Atluri, Peter Chang, Michael Goedecke, Tarek A. Leil
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13248