Quantification of calcified particles in human valve tissue reveals asymmetry of calcific aortic valve disease development

Recent studies indicated that small calcified particles observable by scanning electron microcopy (SEM) may initiate calcification in cardiovascular tissues. We hypothesized that if the calcified particles precede gross calcification observed in calcific aortic valve disease (CAVD), they would exhi...

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Bibliographic Details
Main Authors: Katsumi Yabusaki, Joshua D Hutcheson, Payal Vyas, Sergio Bertazzo, Simon Christopher Body, Masanori Aikawa, Elena Aikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00044/full