TFNR2 in Ischemia-Reperfusion Injury, Rejection, and Tolerance in Transplantation

Tumor necrosis factor receptor 2 (TNFR2) has been shown to play a crucial role in CD4+ T regulatory cells (CD4+Tregs) expansion and suppressive function. Increasing evidence has also demonstrated its role in a variety of immune regulatory cell subtypes such as CD8+ T regulatory cells (CD8+ Tregs), B...

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Bibliographic Details
Main Authors: Araz Kouyoumdjian, Jean Tchervenkov, Steven Paraskevas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.903913/full