Imipenem/Relebactam Ex Vivo Clearance during Continuous Renal Replacement Therapy

(1) Purpose of this study: determination of adsorption and transmembrane clearances (CL<sub>TM</sub>) of imipenem and relebactam in ex vivo continuous hemofiltration (CH) and continuous hemodialysis (CHD) models. These clearances were incorporated into a Monte Carlo Simulation (MCS), to...

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Bibliographic Details
Main Authors: Soo Min Jang, Lenar Yessayan, Michael Dean, Gabrielle Costello, Ravi Katwaru, Bruce A. Mueller
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/10/1184