Chromatographic behavior of co-eluted plasma compounds and effect on screening of drugs by APCI-LCâMS(/MS): Applications to selected cardiovascular drugs
Chromatographic behavior of co-eluted compounds from un-extracted drug-free plasma samples was studied by LCâMS and LCâMS/MS with positive APCI. Under soft gradient, total ion chromatogram (TIC) consisted of two major peaks separated by a constant lower intensity region. Early peak (0.15â0.4Â min) b...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-12-01
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| Series: | Journal of Pharmaceutical Analysis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177914000665 |