Diverse impact of acute and long-term extracellular proteolytic activity on plasticity of neuronal excitability

Learning and memory require alteration in number and strength of existing synaptic connections. Extracellular proteolysis within the synapses has been shown to play a pivotal role in synaptic plasticity by determining synapse structure, function, and number. Although synaptic plasticity of excitator...

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Bibliographic Details
Main Authors: Tomasz eWójtowicz, Patrycja eBrzdak, Jerzy W Mozrzymas
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00313/full