Optimization of Short RNA Aptamers for TNBC Cell Targeting

Optimization of Short RNA Aptamers for TNBC Cell Targeting

Triple-negative breast cancer (TNBC) is an aggressive cancer with limited targeted therapies. RNA aptamers, suitably chemically modified, work for therapeutic purposes in the same way as antibodies. We recently generated 2′Fluoro-pyrimidines RNA-aptamers that act as effective recognition elements fo...

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Bibliographic Details
Main Authors: Simona Camorani, Annachiara d’Argenio, Lisa Agnello, Roberto Nilo, Antonella Zannetti, Luis Exequiel Ibarra, Monica Fedele, Laura Cerchia
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
RNA aptamer
active targeting
aptamer structures
TNBC
Online Access:https://www.mdpi.com/1422-0067/23/7/3511

Internet

https://www.mdpi.com/1422-0067/23/7/3511

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