Homocysteinylated albumin promotes increased monocyte-endothelial cell adhesion and up-regulation of MCP1, Hsp60 and ADAM17.

<h4>Rationale</h4>The cardiovascular risk factor homocysteine is mainly bound to proteins in human plasma, and it has been hypothesized that homocysteinylated proteins are important mediators of the toxic effects of hyperhomocysteinemia. It has been recently demonstrated that homocystein...

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Bibliographic Details
Main Authors: Rosanna Capasso, Irene Sambri, Amelia Cimmino, Sofia Salemme, Cinzia Lombardi, Filomena Acanfora, Ersilia Satta, Donald L Puppione, Alessandra F Perna, Diego Ingrosso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22319627/pdf/?tool=EBI