ArgR of Streptomyces coelicolor Is a Pleiotropic Transcriptional Regulator: Effect on the Transcriptome, Antibiotic Production, and Differentiation in Liquid Cultures

ArgR of Streptomyces coelicolor Is a Pleiotropic Transcriptional Regulator: Effect on the Transcriptome, Antibiotic Production, and Differentiation in Liquid Cultures

ArgR is a well-characterized transcriptional repressor controlling the expression of arginine and pyrimidine biosynthetic genes in bacteria. In this work, the biological role of Streptomyces coelicolor ArgR was analyzed by comparing the transcriptomes of S. coelicolor ΔargR and its parental strain,...

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Bibliographic Details
Main Authors: Alma Botas, Rosario Pérez-Redondo, Antonio Rodríguez-García, Rubén Álvarez-Álvarez, Paula Yagüe, Angel Manteca, Paloma Liras
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
ArgR
arginine
ARG box
S. coelicolor
transcriptomics
sporulation
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00361/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00361/full

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