Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection

Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection

Summary: Individuals with Down syndrome (DS) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how DS influences homeostatic physiology of lung airway, and its reactive responses to pulmonary pathogens. We generated well-differentiated ciliated airway epithelia...

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Bibliographic Details
Main Authors: Samantha N. Thomas, Brian F. Niemeyer, Rocio J. Jimenez-Valdes, Alexander J. Kaiser, Joaquin M. Espinosa, Kelly D. Sullivan, Andrew Goodspeed, James C. Costello, Jonathan K. Alder, Rodrigo Cañas-Arranz, Adolfo García-Sastre, Kambez H. Benam
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Disease
Biological sciences
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014384

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223014384

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