Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

Abstract Extracellular vesicles (EVs) have been shown as key mediators of extracellular small RNA transport. However, carriers of cell-free messenger RNA (cf-mRNA) in human biofluids and their association with cancer remain poorly understood. Here, we performed a transcriptomic analysis of size-frac...

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Main Authors: Hyun Ji Kim, Matthew J. Rames, Florian Goncalves, C. Ward Kirschbaum, Breeshey Roskams-Hieter, Elias Spiliotopoulos, Josephine Briand, Aaron Doe, Joseph Estabrook, Josiah T. Wagner, Emek Demir, Gordon Mills, Thuy T. M. Ngo
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05232-z

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https://doi.org/10.1038/s42003-023-05232-z

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