Current Advance of Therapeutic Agents in Clinical Trials Potentially Targeting Tumor Plasticity

Tumor plasticity refers to tumor cell's inherent property of transforming one type of cell to different types of cells. Tumor plasticity is the main cause of tumor relapse, metastasis and drug resistance. Cancer stem cell (CSC) model embodies the trait of tumor plasticity. During carcinoma prog...

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Bibliographic Details
Main Authors: Xiao-Guang Yang, Lan-Cao Zhu, Yan-Jun Wang, Yan-Yu Li, Dun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00887/full