Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function.

Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function.

C-C motif chemokine receptor-like 2 (CCRL2) is a non-signaling 7 transmembrane receptor that binds chemotactic ligands to shape leukocyte recruitment to sites of inflammation. However, there is a lack of consensus on the ligands that directly bind CCRL2 or their functional impact. Studies with CCRL2...

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Bibliographic Details
Main Authors: Zhenwei Su, Jonathan Brooks, Jeffrey Pelker, Tatyana Andreyeva, Hanna Sobon, Roger Gifford, Matthew Powers, Jing Wang, Corey Dower, Martin Hegen, Dean Messing, Alfredo Darmanin Sheehan, Joseph J Brennan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280590

Internet

https://doi.org/10.1371/journal.pone.0280590

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