Genome-Scale Metabolic Modeling Reveals Metabolic Alterations of Multidrug-Resistant <i>Acinetobacter baumannii</i> in a Murine Bloodstream Infection Model

Genome-Scale Metabolic Modeling Reveals Metabolic Alterations of Multidrug-Resistant <i>Acinetobacter baumannii</i> in a Murine Bloodstream Infection Model

Multidrug-resistant (MDR) <i>Acinetobacter baumannii</i> is a critical threat to human health globally. We constructed a genome-scale metabolic model <i>i</i>AB5075 for the hypervirulent, MDR <i>A. baumannii</i> strain AB5075. Predictions of nutrient utilization a...

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Bibliographic Details
Main Authors: Jinxin Zhao, Yan Zhu, Jiru Han, Yu-Wei Lin, Michael Aichem, Jiping Wang, Ke Chen, Tony Velkov, Falk Schreiber, Jian Li
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Microorganisms
Subjects:
<i>Acinetobacter baumannii</i>
genome-scale metabolic modeling
transcriptomics
bacteremia
RNA-seq
Online Access:https://www.mdpi.com/2076-2607/8/11/1793

Internet

https://www.mdpi.com/2076-2607/8/11/1793

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