Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor

Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor

Trypanosomes evade the immune response through antigenic variation of a surface coat containing variant surface glycoproteins (VSG). They also express invariant surface glycoproteins (ISGs), which are less well understood. Here, Macleod et al. show that ISG65 of T. brucei is a receptor for complemen...

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Bibliographic Details
Main Authors: Olivia J. S. Macleod, Alexander D. Cook, Helena Webb, Mandy Crow, Roisin Burns, Maria Redpath, Stefanie Seisenberger, Camilla E. Trevor, Lori Peacock, Angela Schwede, Nicola Kimblin, Amanda F. Francisco, Julia Pepperl, Steve Rust, Paul Voorheis, Wendy Gibson, Martin C. Taylor, Matthew K. Higgins, Mark Carrington
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32728-9

Internet

https://doi.org/10.1038/s41467-022-32728-9

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