Ophthalmic Bimatoprost-Loaded Niosomal In Situ Gel: Preparation, Optimization, and In Vivo Pharmacodynamics Study

Ophthalmic Bimatoprost-Loaded Niosomal In Situ Gel: Preparation, Optimization, and In Vivo Pharmacodynamics Study

This study aimed at formulating the antiglaucoma agent, Bimatoprost (BMT), into niosomal in situ gel (BMT-ISG) for ocular delivery. Niosomes containing cholesterol/span 60 entrapping BMT were fabricated using a thin-film hydration method. The fabricated niosomes were optimized and characterized for...

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Bibliographic Details
Main Authors: Mohammed F. Aldawsari, Ehssan H. Moglad, Hadil Faris Alotaibi, Hamad M. Alkahtani, El-Sayed Khafagy
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Polymers
Subjects:
bimatoprost
in situ gel
glaucoma
niosomes
ocular delivery
Online Access:https://www.mdpi.com/2073-4360/15/21/4336

Internet

https://www.mdpi.com/2073-4360/15/21/4336

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