Ntrk1 promotes mesangial cell proliferation and inflammation in rat glomerulonephritis model by activating the STAT3 and p38/ERK MAPK signaling pathways

Ntrk1 promotes mesangial cell proliferation and inflammation in rat glomerulonephritis model by activating the STAT3 and p38/ERK MAPK signaling pathways

Abstract Background Mesangial proliferative glomerulonephritis (MsPGN) accounts for a main cause of chronic kidney disease (CKD), chronic renal failure and uremia. This paper aimed to examine the effect of Ntrk1 on MsPGN development, so as to identify a novel therapeutic target for MsPGN. Methods Th...

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Bibliographic Details
Main Authors: Xiongjun Dong, Yingchun Tang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Nephrology
Subjects:
MsPGN
Ntrk1
Glomerulus
Mesangial cel
Proliferation
Inflammation
Online Access:https://doi.org/10.1186/s12882-022-03001-4

Internet

https://doi.org/10.1186/s12882-022-03001-4

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