A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

Intracellular lipopolysaccharide (LPS) triggers the non-canonical inflammasome pathway, resulting in pyroptosis of innate immune cells. In addition to its well-known proinflammatory role, LPS can directly cause regression of some tumors, although the underlying mechanism has remained unknown. Here w...

Full description

Bibliographic Details
Main Authors: Shigetoshi Yokoyama, Yan Cai, Miyuki Murata, Takeshi Tomita, Mitsuhiro Yoneda, Lei Xu, Aprile L Pilon, Raul E Cachau, Shioko Kimura
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
secretoglobin3A2
LPS
syndecan-1
pyroptosis
non-canonical infammasome pathway
cancer cell death
Online Access:https://elifesciences.org/articles/37854

Internet

https://elifesciences.org/articles/37854

Similar Items