Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets

Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets

ABSTRACT Therapeutic inhibition of critical viral functions is important for curtailing coronavirus disease 2019 (COVID-19). We sought to identify antiviral targets through the genome-wide characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins that are crucial for...

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Bibliographic Details
Main Authors: Jiantao Zhang, Qi Li, Ruth S. Cruz Cosme, Volodymyr Gerzanich, Qiyi Tang, J. Marc Simard, Richard Y. Zhao
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
SARS-CoV-2
ORF3a
viral therapeutic target
fission yeast
apoptosis and necrosis
oxidative stress
Online Access:https://journals.asm.org/doi/10.1128/mbio.00169-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00169-22

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