Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility

Summary: Variations in the composition of the intestinal bacterial microbiome correlate with acquisition of some sexually transmitted pathogens. To experimentally assess the contribution of intestinal dysbiosis to rectal lentiviral acquisition, we induce dysbiosis in rhesus macaques (RMs) with the a...

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Bibliographic Details
Main Authors: Alexandra M. Ortiz, Phillip J. Baker, Charlotte A. Langner, Jennifer Simpson, Apollo Stacy, Jacob K. Flynn, Carly E. Starke, Carol L. Vinton, Christine M. Fennessey, Yasmine Belkaid, Brandon F. Keele, Jason M. Brenchley
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723000311

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http://www.sciencedirect.com/science/article/pii/S2211124723000311

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