IDO/kynurenine pathway in cancer: possible therapeutic approaches

Abstract Cancer is one of the leading causes of death in both men and women worldwide. One of the main changes associated with cancer progression, metastasis, recurrence, and chemoresistance is the change in the tumor immune microenvironment, especially immunosuppression. Cancer immunosuppression ap...

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Bibliographic Details
Main Author: Eslam E. Abd El-Fattah
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-022-03554-w