Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation

<p>Abstract</p> <p>Background</p> <p>Worldwide, lung cancer kills more people than breast, colon and prostate cancer combined. Alterations in macrophage number and function during lung tumorigenesis suggest that these immune effector cells stimulate lung cancer growth....

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Bibliographic Details
Main Authors: Malkinson Alvin M, Dwyer-Nield Lori D, Fritz Jason M
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Molecular Cancer
Subjects:
Online Access:http://www.molecular-cancer.com/content/10/1/76