Vitamin B12 does not increase cell viability after hydrogen peroxide induced damage in mouse kidney proximal tubular cells and brain endothelial cells

Vitamin B12 does not increase cell viability after hydrogen peroxide induced damage in mouse kidney proximal tubular cells and brain endothelial cells

Vitamin B12 (B12) is an essential co-factor for two enzymes in mammalian metabolism and can also act as a mimetic of superoxide dismutase (SOD) converting superoxide (O2 •−) to hydrogen peroxide (H2O2). High oral dose B12 decreases renal O2 •− and post-ischemia/reperfusion injury in mice and protect...

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Bibliographic Details
Main Authors: Azraa Ayesha, Edward M Bahnson, Yukako Kayashima, Jennifer Wilder, Phillip K Huynh, Sylvia Hiller, Nobuyo Maeda-Smithies, Feng Li
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Advances in Redox Research
Subjects:
Vitamin B12
Hydrogen peroxide
BU.MPT cells
bEdn.3 cells
Cell viability
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137922000017

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http://www.sciencedirect.com/science/article/pii/S2667137922000017

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