Comprehensive Functional Annotation of Metagenomes and Microbial Genomes Using a Deep Learning-Based Method

Comprehensive Functional Annotation of Metagenomes and Microbial Genomes Using a Deep Learning-Based Method

ABSTRACT Comprehensive protein function annotation is essential for understanding microbiome-related disease mechanisms in the host organisms. However, a large portion of human gut microbial proteins lack functional annotation. Here, we have developed a new metagenome analysis workflow integrating d...

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Bibliografski detalji
Glavni autori: Mary Maranga, Pawel Szczerbiak, Valentyn Bezshapkin, Vladimir Gligorijevic, Chris Chandler, Richard Bonneau, Ramnik J. Xavier, Tommi Vatanen, Tomasz Kosciolek
Format: Članak
Jezik:English
Izdano: American Society for Microbiology 2023-04-01
Serija:mSystems
Teme:
genome
metagenome
orthology
pangenome
deep learning
functional annotation
Online pristup:https://journals.asm.org/doi/10.1128/msystems.01178-22

Internet

https://journals.asm.org/doi/10.1128/msystems.01178-22

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