Quality by Design Based Formulation Study of Meloxicam-Loaded Polymeric Micelles for Intranasal Administration

Quality by Design Based Formulation Study of Meloxicam-Loaded Polymeric Micelles for Intranasal Administration

Our study aimed to develop an “ex tempore” reconstitutable, viscosity enhancer- and preservative-free meloxicam (MEL)-loaded polymeric micelle formulation, via Quality by Design (QbD) approach, exploiting the nose-to-brain pathway, as a suitable tool in the treatment of neuroinflammation. The anti-n...

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Bibliographic Details
Main Authors: Bence Sipos, Piroska Szabó-Révész, Ildikó Csóka, Edina Pallagi, Dorina Gabriella Dobó, Péter Bélteky, Zoltán Kónya, Ágota Deák, László Janovák, Gábor Katona
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
NSAID
nanoDDS
polymeric micelle
quality by design
preformulation study
freeze-drying
Online Access:https://www.mdpi.com/1999-4923/12/8/697

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https://www.mdpi.com/1999-4923/12/8/697

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