Photodynamic effect of three kinds of phycobiliproteins on human mammary cancer line Bcap-37(三种藻胆蛋白对人乳腺癌Bcap-37细胞的光动力杀伤效果)

从高等红藻坛紫菜中提取R-藻红蛋白(R-PE)、R-藻蓝蛋白(R-PC),从低等蓝藻钝顶螺旋藻中提取C-藻蓝蛋白(C-PC).研究10、25、50和100 µg/mL的R-PE、R-PC和C-PC介导的光动力效应对乳腺癌细胞Bcap-37的生存率的影响,MTT法测定结果,探讨这三种藻胆蛋白对癌细胞的光动力杀伤效应与其光敏性质差异的相关性.三种藻胆蛋白的光动力作用对Bcap-37细胞具有显著杀伤并显示出剂量效应,质量浓度在25 µg/mL以上时,杀伤效果依次为:R-PE>R-PC>C-PC;仅用激光处理(497 nm,632.8 nm),Bcap-37细胞的生存率达到88.6% 和9...

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Bibliographic Details
Main Authors: CHENXiao-qiang(陈小强), GONGXing-guo(龚兴国), LIANGQian(梁倩), SHIFeng(史锋), CHENYong(陈勇)
Format: Article
Language:zho
Published: Zhejiang University Press 2005-07-01
Series:Zhejiang Daxue xuebao. Lixue ban
Subjects:
Online Access:https://doi.org/zjup/1008-9497.2005.32.4.438-441