RUNX3 overexpression inhibits normal human erythroid development

Abstract RUNX proteins belong to a family of transcription factors essential for cellular proliferation, differentiation, and apoptosis with emerging data implicating RUNX3 in haematopoiesis and haematological malignancies. Here we show that RUNX3 plays an important regulatory role in normal human e...

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Bibliographic Details
Main Authors: Ana Catarina Menezes, Christabel Dixon, Anna Scholz, Rachael Nicholson, Adam Leckenby, Aleksandra Azevedo, Sarah Baker, Amanda F. Gilkes, Sara Davies, Richard L. Darley, Alex Tonks
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05371-z